这两个单词意思都一样，都是无论什么的意思 但no matter what只能放在句首，在句中，只能用whatever 例如with the money , you can buy______you want就只能填whatever,不能填no matter what如要改成no matter who的话，应作：No matter what you want,I'll buy it for you.
不论是“疑问代词 + ever ”还是“疑问副词 + ever ”，其意义都是“不管 / 无论 + 该疑问词的本义”。
1. “疑问代词 + ever”可引导两种类型的从句，即让步状语从句和名词性从句（主语从句、宾语从句）。
（1）引导让步状语从句。此时 whatever / whoever / whichever 分别等于“ no matter + what / who / which”。例如：
Whatever happened， he wouldn't say a word. = No matter what happened， he wouldn't say a word.
Whoever says so， it is wrong. = No matter who says so， it is wrong.
Whichever dictionary you （may） take， you will have to pay at least 20 dollars. = No matter which dictionary you （may） take， you will have to pay at least 20 dollars. Whoever smokes here will be punished. （主语从句）
Beggars will eat whatever they are given. （宾语从句）
Whichever he likes will be given to him. （主语从句）
论是“疑问代词 + ever ”还是“疑问副词 + ever ”，其意义都是“不管 / 无论 + 该疑问词的本义”。
  1. “疑问代词 + ever”可引导两种类型的从句，即让步状语从句和名词性从句(主语从句、宾语从句)。
  (1)引导让步状语从句。此时 whatever / whoever / whichever 分别等于“ no matter + what / who / which”。例如：
  Whatever happened， he wouldn't say a word. = No matter what happened， he wouldn't say a word.
  Whoever says so， it is wrong. = No matter who says so， it is wrong.
  Whichever dictionary you (may) take， you will have to pay at least 20 dollars. = No matter which dictionary you (may) take， you will have to pay at least 20 dollars.
  注意：这类从句中应用一般现在时表将来，从句中也常用情态动词 may / might .
  (2)引导名词性从句。例如：
  Whoever smokes here will be punished. (主语从句)
  Beggars will eat whatever they are given. (宾语从句)
  Whichever he likes will be given to him. (主语从句)
  You may invite whoever / whomever you like. (常用 whoever 代替 whomever)
  此时它们都不能换成“ no matter + 疑问词”的形式，但 whoever 等于 anyone who， whatever 等于 anything that.
  2. “疑问副词 +ever ”： wherever / whenever / however 一般只能引导一种类型的从句，即让步状语从句，此时它们分别等于“ no matter + where / when / how ”。例如：
wrong是什么意思  Wherever he goes (may go). I'll follow him. = No matter where he goes (may go)，I'll follow him.
  Whenever I wisited him， he was always busy working. = No matter when I visited him， he was always busy working.
  However late he is， his mother will wait for him to have dinner together. = No matter how late he is， his mother will wait for him to have dinner together.
  注意：当 however 用作连接副词时也可引导名词性从句，而 whenever/ wherever 则不能引导名词性从句。例如：
  I'll give you however much money you need. (宾语从句，此时 however 不能改成 no matter how )。
  3. 另外， whatever / whichever / whoever 与 whenever / wherever / however 分别可相当于 what / which / who 与 when / where / how 的强调式，引起的特殊疑问句往往是简单句，与原疑问词的意思、用法完全相同，只是表达的语气更为强烈，翻译时可加上“到底；究竟”等。例如：
  What(ever) are you doing ？ 你(到底)在干什么？
  Which(ever) do you want to buy ？ 你(究竟)要买哪一个？
  Who(ever) told you such a foolish story？ (究竟)是谁讲给你这么蠢的事？
  When(ever) can I enjoy a long vacation？ (究竟)什么时候才能给我放个长假呢？
  Where(ever) did you leave your dictionary？ 你(究竟)把词典放哪儿了？
  How(ever) did you collect so much money？ 你(到底)是怎样筹到这么多钱的？
上述三道高考题涉及到however和whatever引导从句时的用法，下面将就此分别加以归纳。
  1. However的用法主要有以下两点：
  (1) 用作连接副词，相当于no matter how，引导让步状语从句，意思是“不管怎样……”“无论如何……”，具体结构有以下两种：
第一, “however+形容词+主语+系动词”。例如：
① However busy he was, he might have given you some help. 
② I'll come however busy I am.     
第二, “ however+副词+主语+谓语”，例如.：
However fast he run, I can always catch up with him. 
(2) 用作连词，引导让步状语从句，意思是“怎么样都行”。例如：
In one’s own home one can acts however he wishes.
2. Whatever的用法主要有以下两点：
( 1 ) 引导名词性从句，相当于anything that，意思是“所……的任何事情”，在语气上比what
更加强调。例如：
①    Whatever she did was right.
② Take whatever you want. 
（2）引导让步状语从句，相当于no matter what，意思是“无论什么”，“不管什么”，whatever在从句中可作主语、宾语、表语或定语。例如
①    Whatever happens，you mustn’t lose your heart. 
②    Whatever you do，do it well.
③    Whatever I am，it is useful to know foreign languages. 
④    You have to go on whatever difficulties you meet.
三. however, whatever的同类词语
根据上述however 和whatever的构词形式，笔者把学过的这些词归为两大类：
第一类： however，whenever，wherever，作连词或者副词, 相当于“no matter + 特殊疑问词”，只用于引导让步状语从句，不能用于引导名词性从句。例如： 
① Whenever we see him，we speak to him.
    ② wherever you go, please let me know.
③ However difficult the job is, he never lose heart.
第二类：whatever，whichever，whoever，作代词或者形容词，既用于引导让步状语从句，也用于引导名词性从句。例如：
① Keep calm, whatever happens
②  Don’t give children whatever they want.
    ③ Believe that whichever you choose is the best.