专利名称：STRUCTURAL CAROTENOID ANALOGS FOR THE INHIBITION AND AMELIORATION OF
DISEASE
发明人：LOCKWOOD, Samuel, Fournier,O'MALLEY, Sean,WATUMULL, David, G.,HIX, Laura,
M.,JACKSON, Henry,NADOLSKI, Geoff
申请号：EP03772051.3
申请日：20030729
公开号：EP1532108A2
公开日：
20050525
专利内容由知识产权出版社提供
摘要：A method for inhibiting and/or ameliorating the occurrence of diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals in a subject whereby a subject is administered a carotenoid structural analog, either alone or in combination with another carotenoid analog, or co-antioxidant formulation. The analog or analog combination is administered such that the subject's risk of experiencing diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals may be thereby reduced. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of ischemia-reperfusion injury. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of liver disease. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of cancer. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of cardiac arrhythmia and/or sudden cardiac death. The
reactive oxygen species是什么意思analog or analog combination may be administered to a subject for the inhibition and/or amelioration of
any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In one embodiment, a water-soluble
and/or water-dispersible astaxanthin analog is particularly effective. This invention further includes pharmaceutical compositions comprising structural carotenoid analogs either alone or in combination.
申请人：Hawaii Biotech, Inc.
地址：Suite 236,99-193 Aiea Heights Drive Aiea, HI 96701 US
国籍：US
代理机构：Casalonga, Axel
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