ACUTE DISSEMINATED ENCEPHALOMYELITIS
(ADEM)
期刊名称： Neuropediatrics
作者： A. Alrumayan,M. Aldubayee
年份： 2006年
期号： 第1期
关键词： ADEM;MS;Cytokines;Chemokines;Neuroimagingcharacterise
摘要：Objective: To describe the epidemiologic, clinical, neuroimaging, laboratory features, treatment; and outcome in a cohort of children with acute disseminated encephalomyelitis (ADEM). Introduction:Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disorder of the central nervous system characterised by multifocal white matter involvement due to an autoimmune path
ology. Diffuse neurological signs along with multifocal lesions in brain and spinal cord characterise the disease. It usually follows an infection or vaccination. ADEM is a monophasic disease, 80% have good recovery with no neurologic deficit, Current treatment with pulse steroid therapy Vs IVIG. Methods: A 10-years retrospective chart review of children with the diagnosis of ADEM was conducted at King Abdulaziz Medical City (KAMC). Results:Thirteen
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